Chemical Constituents of Ajuga parviflora

نویسندگان

  • Hafiz Rub Nawaz
  • Abdul Malik
  • Pir Muhammad
  • Saeed Ahmed
  • Muhammad Riaz
چکیده

Two new antifungal withanolides, (1) and (2) have been isolated from the defatted methanolic extract of Ajuga parviflora. Their structures were established as 3/3,17/3,20-trihydroxyl-oxo-(20/?, 22/?)-witha-5,14,24-trienolide (1), 28-hydroxy-14,20-epoxy-l-oxo-(22/?)-witha2,5,24-trienolide (2) on the basis of spectroscopic data including two dimensional NMR tech­ niques. The pyrrolizidine alkaloids senecionine (3) and integerrimine (4) are also reported for the first time from A. parviflora.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Antibacterial Properties of Ajuga chamaecistus Subsp. Scoparia and Chemical Composition of its Oils

In the present study, we reported the essential oils chemical composition and antibacterial activities of the aerial parts of Ajuga chamaecistus Ging. ex Benth. Subsp. Scoparia (Boiss.) Rech.f. thatwere collected duringMay 2013 and April 2014 and extracted by SDE (simultaneous distillation–extraction) and Clevenger apparatus. GC/MS analysis of the plant essential oils led to the identification ...

متن کامل

Structures of two new phenolic glycosides, kaempferiaosides A and B, and hepatoprotective constituents from the rhizomes of Kaempferia parviflora.

Two new phenolic glycosides, kaempferiaosides A and B were isolated from the rhizomes of Kaempferia parviflora (Zingiberaceae) together with 24 known compounds. Their structures including absolute stereochemistry were elucidated on the basis of chemical and spectroscopic evidence. Among the isolates, 5,3'-dihydroxy-3,7,4'-trimethoxyflavone showed higher activity than silybin, a commercial hepat...

متن کامل

Major constituents and cytotoxic effects of Ajuga chamaecistus ssp. tomentella.

The n-butanolic fraction of a methanolic extract (80%) from aerial parts of Ajuga chamaecistus ssp. tomentella was analysed using different chromatographic methods. Column (CC) and high-performance liquid chromatography (HPLC) were used for isolation and purification. 13C, H NMR, H-H COSY, HSQC, HMBC, and ESI-MS were employed for identification of the compounds isolated from this fraction. The ...

متن کامل

Study of Antibacterial Effects of Different Fractions of Leaves Extract of Ajuga Chamaecistus Ging. Subsp. Scoparia (Bioss) Rech. f. and Bioautography of Effective Fraction

Background & Aims: Today, the emergence of antimicrobial resistance against conventional antibiotics is increasing. Many researchers consider plants with antimicrobial properties as a good alternative. In this study, the antimicrobial activity of Ajuga chamaecistus Ging. Subsp. Scoparia (Bioss) Rech. f. on 8 bacterial strains wasinvestigated. Methods: The leaf extract was prepared by methanolic...

متن کامل

Quality evaluation of Kaempferia parviflora rhizome with reference to 5,7-dimethoxyflavone

Kaempferia parviflora Wall. ex Baker is a medicinal plant found in the upper Northeastern regions of Thailand, which belongs to Zingiberaceae family. The present study aims to investigate the standardization parameters, to analyze chemical constituents of volatile oil by gas chromatography-mass spectrometry, and to determine the content of 5,7-dimethoxyflavone in K. parviflora rhizomes by thin-...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2000